Associations between Smoking, Intrauterine Device Uptake, and Ectopic Pregnancy: A Meta Analysis

Background: Ectopic pregnancy is an import­ant cause of maternal morbidity and mortality, estimated to occur in approximately 1-2% pregnancies worldwide. Smoking history using intrauterine devices are risk factors for ectopic pregnancy. This study aims estimate the magnitude relationship between smoking a on incidence based number previous primary studies. Subjects Method: syste­matic review meta-analysis. The articles used this were obtained from several databases, including: PubMed, Google Scholar, Science Direct which published 2000-2020. inclusion criteria full text with Case Control design. keywords search as follows: AND multivariate; use device OR cigarette “use device” “ectopic pregnancy” “tubal multivariate. Articles collected PRISMA flow diagrams analyzed Review Manager 5.3. Results: A meta-analysis 7 showed that women reproductive age who smoked had 2.20 times compared did not smoke (aOR= 2.20; 95% CI= 1.45 3.34; p= 0.002). 9 2.28 2.28; 1.74 2.98; p<0.001). Conclusion: increase Keywords: smoking, contracep­tives, pregnancy, Correspondence:  Ridha Rossela Yanuari. Masters Program Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 085747311182 Journal Maternal Child Health (2021), 06(04): 388-399 https://doi.org/10.26911/thejmch.2021.06.04.01